There is deterioration of the quality of life of those with IgAN
Without effective management of IgA Nephropathy, it can have negative effects on the emotional and psychosocial aspects of the life of those affected.1 In addition, the symptoms and the side effects of medication limit the capacity of IgA Nephropathy patients to participate in activities that are important to them, such as sport and social interaction.1
Moreover, the mortality rate of individuals with moderate to high grade IgA Nephropathy is higher by a factor of two. In a large-scale cohort study (N=665) that was conducted over a mean duration of 11.8 years (actual duration: 0.0-20.8 years), the IgA Nephropathy death rate among patients was found to be twice as high as that among the general population.2
The progression of IgA Nephropathy can have significant negative impacts on the future plans of those affected.
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