IgA Nephropathy: when the gut causes inflamed kidneys
Berger's disease, also known as immunoglobulin A Nephropathy (IgAN), is the most common form of glomerulonephritis, a disorder in which there is non-bacteria-related inflammation of the filtering units (glomeruli) of the kidneys. Whilst IgAN originates in the gut1, it is the kidneys that are damaged. Ultimately, 25-30% of those with IgA Nephropathy develop end-stage renal disease within 20-25 years, requiring dialysis or even kidney transplantation.2 At present, the treatment options for IgA Nephropathy are limited and new forms of treatment approaches are constantly being explored, it is hoped these could at least slow disease progression.
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